Table 2.
3 Months | 6 Months | |||
---|---|---|---|---|
Control | Vit.D- | Control | Vit.D- | |
n = 7; m = 3 | n = 10; m = 3 | n = 7; m = 3 | n = 9; m = 3 | |
Body weight (g) | 358 ± 18 | 401 ± 15 * | 448 ± 19 | 498 ± 13 * |
Food intake (mg 100 g−1) | 8.6 ± 1.2 | 11.9 ± 1.2 * | 10.3 ± 1.2 | 13.6 ± 1.0 * |
Water intake (mL 100 g−1) | 8.3 ± 1.2 | 11.3 ± 1.8 * | 9.8 ± 1.2 | 13.9 ± 1.2 * |
V (mL 100 g−1) | 6.3 ± 1.8 | 8.5 ± 2.45 * | 7.2 ± 1.8 | 9.8 ± 2.3 * |
U (mOsm kg H2O−1) | 1.458 ± 135 | 1.270 ± 108 * | 1.711 ± 145 | 1.250 ± 129 * |
U Na+/Cr | 2.8 ± 0.8 | 3.4 ± 0.5 * | 2.9 ± 0.6 | 3.9 ± 0.7 * |
U K+/Cr | 3.6 ± 0.3 | 4.3 ± 0.4* | 3.7 ± 0.3 | 4.5 ± 0.4* |
SBP (mmHg) | 121 ± 1.3 | 133 ± 1.8 * | 123 ± 1.2 | 141 ± 1.6 * |
ALB (µg 24 h−1) | 0.4 (0.3; 0.6) | 0.6 (0.3; 0.7) | 0.6 (0.4; 0.6) | 0.7 (0.5; 0.8) |
The 24-h urinary volume (V), urinary osmolality (U), urinary excretion Na+(U Na+), urinary excretion K+ (U K+), Cr (creatinine) level, albuminuria (ALB) and systolic blood pressure (SBP) of 3- and 6-month-old pups in the control and Vit.D- groups. Data are expressed as the median and interquartile range (25th–75th) (ALB) or the mean ± SEM (Body weight, Food intake, SBP, V, U, U Na+, and U K+). n = number of animals, m= number of litters. * p < 0.05 compared with controls of the same age.