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Cytotoxic effects of 1 and 2 expressed by half maximal inhibitory concentration (IC50) values.
| Compounds | IC50 (µM) a | ||
|---|---|---|---|
| HT-29 | OVCAR-3 | MM. 1S | |
| 1 | 8 ± 0.8 | 7 ± 0.3 | 9 ± 0.7 |
| 2 | 12.5 ± 0.3 | 9 ± 0.6 | 11 ± 0.9 |
a Values are means of three independent experiments. human colon cancer cell line: HT-29; human ovarian cancer cell line: OVCAR-3; multiple myeloma cell line: MM.1S.
