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Effect of endogenous L5 and V5 on cellular senescence in vivo. Agarose gel electrophoresis (A) and Western blot analysis (B) with anti-ApoB100 show the difference between blood serum from wild-type (WT) and ApoE−/− mice fed with a high-fat diet for 15 weeks. Oil Red O (C) and senescence-associated β-galactosidase (SA-β-Gal) (D) staining of aortas from WT and ApoE−/− mice fed with a high-fat diet. WT (B57CL/6) mice were used as controls.
