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. 2019 Aug 7;8(8):1178. doi: 10.3390/jcm8081178

Figure 2.

Figure 2

Visfatin Interaction with Osteoarthritis (OA) and Osteoporosis (OP) Risk Factors. Intracellular visfatin synthesis and its enzymatic activity. Intracellular visfatin synthesis and its enzymatic activity. Among the shared risk factors between OA and OP, stand inflammation, and several metabolic alterations (type 2 diabetes mellitus (T2DM), obesity, and insulin resistance). Interestingly, both risk factors are associated to visfatin, a life-essential enzyme. Nicotinamide (NA); nicotinamide mononucleotide adenyltransferase (NMA); nicotinamide adenine dinucleotide (NAD+).