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. 2019 Aug 8;11(8):466. doi: 10.3390/toxins11080466

Table 2.

Estimations of the parameters (Fabs and rate constants) modelled as fixed effects belonging to model II (Figure 3) applied for the single dose administration of DON3G.

Value Standard Error
Fabs 0.53 0.04
KlaD 0.67 0.79
KmD-3-GlcA 0.13 0.15
KmD-15-GlcA 0.38 0.45
KeD3G 0.018 0.017
KeD 0.17 0.20
KeD-3-GlcA 0.49 0.07
KeD-15-GlcA 0.49 0.07

KlaD = lumped absorption rate constant of DON (including hydrolysis of DON3G to DON), KeD3G = excretion rate constant of DON3G