Table 4.
Linear trend of single biomarker concentrations on linear regression model of the severity score, adjusted for age and gender.
| NAFLD Score (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Parameter (Mean ± Standard Error) | Sample Size | 0 (80.73%) | 1 (0.26%) | 2 (0.78%) | 3 (5.21%) | 4 (4.69%) | 5 (2.60%) | 6 (5.73%) | p-Value for Trend |
| White cells (n/106 L) | 356 | 6670.42 ± 110.33 | 6480.77 ± 1875.31 | 6752.17 ± 1083.65 | 7163.04 ± 485.90 | 6149.92 ± 472.72 | 6610.26 ± 592.73 | 7199.73 ± 415.29 | <0.001 |
| Hemoglobin (g/dL) | 356 | 13.57 ± 0.07 | 13.25 ± 1.22 | 14.19 ± 0.70 | 13.97 ± 0.31 | 13.85 ± 0.31 | 14.09 ± 0.38 | 14.32 ± 0.27 | <0.001 |
| Albumin (g/L) | 353 | 4.16 ± 0.14 | 3.95 ± 0.12 | 3.73 ± 0.12 | 3.52 ± 0.15 | 3.31 ± 0.19 | 3.09 ± 0.23 | 2.88 ± 0.28 | <0.001 |
| Creatinine (μg/L) | 353 | 0.78 ± 0.01 | 0.75 ± 0.16 | 0.94 ± 0.09 | 0.86 ± 0.04 | 0.70 ± 0.04 | 0.76 ± 0.05 | 0.75 ± 0.03 | <0.001 |
| Serum uric acid (mg/dL) | 329 | 4.38 ± 0.07 | 4.29 ± 1.11 | 5.30 ± 0.64 | 4.60 ± 0.30 | 4.90 ± 0.29 | 5.33 ± 0.37 | 4.65 ± 0.26 | <0.001 |
| GPT (U/L) | 351 | 28.78 ± 1.34 | 27.08 ± 22.57 | 28.43 ± 13.04 | 27.03 ± 5.68 | 36.00 ± 5.69 | 46.13 ± 7.13 | 39.12 ± 5.00 | <0.001 |
| GGT (U/L) | 340 | 25.15 ± 1.32 | 18.51 ± 21.79 | 26.94 ± 12.59 | 29.20 ± 5.48 | 35.13 ± 5.49 | 31.65 ± 7.26 | 36.55 ± 4.83 | <0.001 |
| Total cholesterol (mg/dL) | 350 | 200.82 ± 2.26 | 239.82 ± 38.03 | 195.66 ± 21.97 | 198.30 ± 9.57 | 190.83 ± 9.59 | 211.85 ± 12.02 | 200.24 ± 8.63 | <0.001 |
| HDL (mg/dL) | 343 | 56.93 ± 0.78 | 71.25 ± 12.99 | 44.44 ± 7.50 | 51.49 ± 3.27 | 47.99 ± 3.27 | 50.27 ± 4.10 | 48.25 ± 2.95 | <0.001 |
| Triglycerides (mg/dL) | 350 | 114.85 ± 3.93 | 93.86 ± 66.09 | 145.19 ± 38.19 | 134.57 ± 16.63 | 134.84 ± 16.66 | 186.33 ± 20.89 | 152.40 ± 15.00 | <0.001 |
| Fasting plasma glucose (mg/dL) | 354 | 100.55 ± 1.54 | 96.50 ± 26.04 | 97.09 ± 15.05 | 93.09 ± 6.55 | 106.45 ± 6.56 | 102.26 ± 8.23 | 94.03 ± 5.89 | <0.001 |
| Insulin (mIU/L) | 323 | 12.70 ± 0.90 | 6.00 ± 14.59 | 16.81 ± 8.43 | 13.44 ± 3.78 | 12.46 ± 3.68 | 19.20 ± 4.86 | 13.56 ± 3.47 | <0.001 |
| TSH (µIU/mL) | 342 | 1.98 ± 0.08 | 1.61 ± 1.32 | 1.74 ± 0.76 | 2.56 ± 0.33 | 2.39 ± 0.33 | 1.79 ± 0.44 | 1.44 ± 0.31 | <0.001 |
Abbreviations: GPT: glutamic pyruvic transaminase; GGT: Gamma-glutamyl transferase; NAFLD: non-alcoholic fatty liver disease; TSH: thyroid stimulating hormone.