Table 3.
Data extracted from the selected studies for meta-analysis. The total number of patients analyzed and those with compatible antibody tests or biopsy are shown.
| First Author | Infertility | Unexplained Infertility | Recurrent Miscarriage | Control Group | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total N | Anti-TG2 | EMA | Biopsy | Total N | Anti-TG2 | EMA | Biopsy | Total N | Anti-TG2 | EMA | Biopsy | Total N | Anti-TG2 | EMA | Biopsy | |
| Wilson [17] | 77 | - | - | 2 | - | - | - | - | - | - | - | - | - | - | - | - |
| Collin [9] | 200 | - | - | 4 | 98 | - | - | 4 | 50 | - | - | 0 | 150 | - | - | 0 |
| Kolho [18] | 192 | - | 2 | - | 47 | - | 1 | - | 63 | - | 1 | - | 51 | - | 1 | 1 |
| Meloni [19] | 99 | - | 4 | 3 | 25 | - | 2 | 1 | - | - | - | - | 1607 | - | - | 17 |
| Vancikova [10] | 363 | 4 | 1 | - | 275 | 3 | 0 | - | - | - | - | - | 1312 | 92 | 6 | - |
| Fasano [12] | 48 | - | 3 | - | 48 | - | 3 | - | - | - | - | - | 2069 | - | 15 | - |
| Shamaly [20] | 192 | 4 | 5 | 5 | 192 | 4 | 5 | 5 | - | - | - | - | 210 | 2 | 0 | 1 |
| Tiboni [14] | 200 | 5 | 3 | 5 | 53 | 0 | 0 | - | - | - | - | - | 200 | 2 | 1 | 2 |
| Bustos [21] | 118 | 3 | - | - | - | - | - | 118 | 3 | - | - | 125 | 0 | - | - | |
| Jackson [22] | 121 | 1 | 1 | - | 121 | 1 | 1 | - | - | - | - | - | - | - | - | - |
| Kumar [11] | 334 | 20 | 16 | - | 230 | 13 | 11 | - | 104 | 7 | 5 | - | 305 | 4 | 3 | - |
| Hogen Esch [23] | 654 | 5 | 5 | - | 351 | 2 | 2 | - | - | - | - | - | 716 | 2 | 2 | - |
| Choi [13] | 188 | 3 | 3 | 4 | 51 | 2 | 2 | 3 | - | - | - | - | - | - | - | - |
| Khoshbaten [24] | 100 | 8 | - | 3 * | 100 | 8 | - | 3 * | - | - | - | - | 200 | 4 | - | 0 |
| Sharshiner [25] | 116 | 1 | 0 | - | - | - | - | - | 116 | 1 | 0 | - | 116 | 1 | 1 | - |
| Machado [26] | 170 | 6 | 3 | 2 ** | 29 | 3 | 3 | 2 ** | - | - | - | - | - | - | - | - |
| Karaca [27] | 65 | 0 | 0 | 0 | 65 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
| Sarikaya [28] | 45 | 1 | - | - | - | - | - | - | 45 | 1 | - | - | 41 | 3 | - | - |
| Sabzebari [29] | 100 | 8 | - | 7 | 100 | 8 | - | 7 | - | - | - | - | - | - | - | - |
| Gunn [30] | 393 | 1 | - | - | 197 | 1 | - | - | - | - | - | - | - | - | - | - |
| Juneau [31] | 995 | 24 | 22 | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Grode [32] | 457 | 4 | - | 1 | - | - | - | - | - | - | - | - | - | - | - | - |
| Kutteh [33] | 708 | 9 | 6 | - | - | - | - | - | 708 | 9 | 6 | - | 100 | 1 | 1 | - |
* Biopsy performed in 3 anti-TG2 positive women; ** biopsy performed in 5 seropositive women.