Table 1.

Definition of the endpoints “prevention success” and “prevention failure” for the IPP study.

Prevention success Improvement of one risk factor without deterioration of another Prevention failure Deterioration of one risk factor without improvement of another
Risk factors	Improvement	Deterioration
Smoking	Smoking cessation (at least for 4 weeks at evaluation, controlled by serum cotinine levels)	New or recurrent active smoking
LDL cholesterol	Reduction < 5 mg/dL	Increase ≥ 5 mg/dL
Physical inactivity	Increase of caloric expenditure ≥ 500 kcal/week (leisure time moderate or vigorous physical activity assessed by IPAQ)	Decrease of caloric expenditure ≥ 500 kcal/week