Table 4.

Top ten KEGG pathways enriched with the differentially expressed genes.

KEGG Pathway	Count	p-Value	Bonferroni p-Value	Gene Symbols
mmu03010:Ribosome	94	3.91 $\times {10}^{-62}$	1.08 $\times {10}^{-59}$	RPL18, RPL17, RPL36A, RPL19, RPL14, RPL13, RPL15, RPLP2, RPS27L, RPL22L1, etc.
mmu03040:Spliceosome	54	3.72 $\times {10}^{-22}$	1.02 $\times {10}^{-19}$	SRSF1, LSM6, U2AF2, SNRPD3, LSM7, SNRPD1, SNRPD2, RBM8A, PCBP1, U2AF1, etc.
mmu01130:Biosynthesis of antibiotics	52	5.87 $\times {10}^{-11}$	1.61 $\times {10}^{-8}$	SC5D, LDHA, EHHADH, PGAM1, OGDH, CMBL, PKM, IDH3G, PDHA1, CAT, etc.
mmu03050:Proteasome	21	3.95 $\times {10}^{-10}$	1.09 $\times {10}^{-7}$	SHFM1, PSMB5, PSMA2, PSMB4, PSMA1, PSMD14, PSMB7, PSMB6, PSMC5, PSMB1, etc.
mmu01200:Carbon metabolism	33	5.49 $\times {10}^{-9}$	1.51 $\times {10}^{-6}$	ALDOA, ALDOC, EHHADH, ALDOB, PGAM1, OGDH, GPI1, ACAT1, PKM, TPI1, etc.
mmu00010:Glycolysis /Gluconeogenesis	23	3.32 $\times {10}^{-8}$	9.13 $\times {10}^{-6}$	ALDOA, LDHA, ALDOC, HKDC1, ALDOB, FBP1, PGAM1, PFKP, FBP2, GPI1, etc.
mmu01100:Metabolic pathways	168	7.42 $\times {10}^{-8}$	2.04 $\times {10}^{-5}$	CYP2C66, CYP2C65, GDA, LDHA, SC5D, CNDP2, EHHADH, CYP2C68, DTYMK, PGAM1, etc.
mmu00480:Glutathione metabolism	20	1.51 $\times {10}^{-7}$	4.16 $\times {10}^{-5}$	GSTA1, GSTA2, ODC1, GSTA4, SRM, GGT1, ANPEP, GSTM6, GSTM1, GPX2, etc.
mmu05204:Chemical carcinogenesis	26	3.58 $\times {10}^{-7}$	9.85 $\times {10}^{-5}$	CYP2C66, CYP2C65, CYP3A25, CYP2C68, GSTM6, GSTM1, GSTM3, CBR1, GSTM4, ADH1, etc.
mmu01230:Biosynthesis of amino acids	22	2.30 $\times {10}^{-6}$	6.33 $\times {10}^{-4}$	ALDOA, SHMT2, MAT2A, ALDOC, ALDOB, PFKP, PGAM1, CPS1, IDH3A, PKM, etc.