Table 5.

Top five Gene Ontology (GO) terms in each GO domain enriched in differentially expressed genes.

Gene Ontology	Count	p-Value	Bonferroni Correction	Gene Symbols
GO:BP ${}^a$: GO:0006412 translation	145	3.83 $\times {10}^{-74}$	1.34 $\times {10}^{-70}$	RPL18, RPL17, RPL36A, RPL19, RPL14, RPL13, RBM3, EIF5, RPL15, EIF5A, etc.
GO:BP ${}^a$: GO:0008380 RNA splicing	67	2.68 $\times {10}^{-26}$	9.38 $\times {10}^{-23}$	RALY, SRSF1, LSM6, SNRPD3, U2AF2, SNRPD1, SYNCRIP, SNRPD2, YBX1, NONO, etc.
GO:BP ${}^a$: GO:0006397 mRNA processing	75	3.36 $\times {10}^{-24}$	1.18 $\times {10}^{-20}$	RALY, SRSF1, LSM6, U2AF2, SNRPD3, SNRPD1, SYNCRIP, SNRPD2, YBX1, NONO, etc.
GO:BP ${}^a$: GO:0055114 oxidation-reduction process	101	2.51 $\times {10}^{-17}$	8.79 $\times {10}^{-14}$	SC5D, LDHA, EHHADH, OGDH, UQCR10, IDH3G, CPOX, PDHA1, HADH, NQO1, etc.
GO:BP ${}^a$: GO:0006413 translational initiation	25	1.07 $\times {10}^{-15}$	3.88 $\times {10}^{-12}$	ABCE1, EIF5, DENR, EIF1A, LARP1, EIF4B, EIF4G2, EIF3D, EIF3A, EIF3B, etc.
GO:CC ${}^b$: GO:0030529 intracellular ribonucleoprotein complex	151	1.35 $\times {10}^{-99}$	9.24 $\times {10}^{-97}$	RPL18, MRPL40, RALY, SRP14, RPL17, MRPL42, RPL19, RPL14, RPL13, SNRPD3, etc.
GO:CC ${}^b$: GO:0070062 extracellular exosome	401	3.28 $\times {10}^{-81}$	2.26 $\times {10}^{-78}$	PRDX5, PRDX2, RPS2, SYNGR2, PTMA, RPS3, SLC1A5, RHOC, TREH, CAT, etc.
GO:CC ${}^b$: GO:0005840 ribosome	101	3.93 $\times {10}^{-73}$	2.70 $\times {10}^{-70}$	RPL18, MRPL40, RPL17, RPL36A, MRPL42, RPL19, RPL14, RPL13, RPL15, RPLP2, etc.
GO:CC ${}^b$: GO:0022625 cytosolic large ribosomal subunit	50	1.34 $\times {10}^{-36}$	9.19 $\times {10}^{-34}$	RPL18, RPL17, RPL36A, RPL19, RPL14, RPL13, RPL15, RPLP2, RPL22L1, RPLP0, etc.
GO:CC ${}^b$: GO:0005730 nucleolus	148	1.01 $\times {10}^{-34}$	6.91 $\times {10}^{-32}$	RPL18, MRPL40, RPL19, LSM6, RBM3, MORF4L2, CBX5, NONO, EBNA1BP2, IMP3, etc.
GO:MF ${}^c$: GO:0044822 poly(A) RNA binding	295	5.08 $\times {10}^{-115}$	6.64 $\times {10}^{-112}$	RPS25, RPS26, RPS28, PABPC1, RPS20, RPS21, RPS23, HNRNPAB, RPS24, DHX9, etc.
GO:MF ${}^c$: GO:0003735 structural constituent of ribosome	104	2.15 $\times {10}^{-56}$	2.81 $\times {10}^{-53}$	RPL18, RPL17, RPL36A, RPL19, RPL14, RPL13, RPL15, RPLP2, RPS27L, RPL22L1, etc.
GO:MF ${}^c$: GO:0003723 RNA binding	165	5.82 $\times {10}^{-47}$	7.61 $\times {10}^{-44}$	RPL18, RALY, SRP14, RPL13, SNRPD3, U2AF2, LSM6, RBM3, LSM7, SNRPD1, etc.
GO:MF ${}^c$: GO:0003729 mRNA binding	46	6.85 $\times {10}^{-21}$	8.95 $\times {10}^{-18}$	SRSF1, TRA2B, RPL35, RPS2, YBX1, RPS3, HNRNPA3, RPS26, MRPL13, EIF3A, etc.
GO:MF ${}^c$: GO:0098641 cadherin binding involved in cell-cell adhesion	64	4.66 $\times {10}^{-20}$	6.09 $\times {10}^{-17}$	HSP90AB1, LDHA, RPL14, RPL15, EIF5, PDLIM1, RANGAP1, RPS2, LARP1, BZW2, etc.

${}^a$ Biological Process, ${}^b$ Cellular Components, ${}^c$ Molecular Function.