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. 2019 Aug 1;11(8):373. doi: 10.3390/pharmaceutics11080373

Figure 4.

Figure 4

Effects of curcumin and CurDD on (A) serum vascular endothelium growth factor (VEGF) secretion and (B) cyclooxygenase-2 (COX-2) expression from tumor tissue of a HepG2-transplanted tumor in nude mice and in the treatment groups at 21 days after treatment. (Data are presented as means ± SD (n = 8); a p < 0.05 compared to control group, b p < 0.05 compared to HepG2 group, c p < 0.05 compared to HepG2+Cur 300 mg/kg group, d p < 0.05 compared to HepG2+Cur 3000 mg/kg group, and e p < 0.05 compared to HepG2+CurDD 500 mg/kg group).