Table 2.

Currently commercialized bone xenografts from mammal origin. The last four rows include the commercialized combinations of polymers or extracellular matrix proteins with mammalian origin xenografts ².

Brand Name	Company	Compositional Details	Intended Use
Bio-Oss®	Geistlich	Bovine deproteinized bone	Periodontal, oral, and maxillofacial surgery
Orthoss®	Geistlich	Bovine derived bone substitute made from highly purified bone mineral	Filling of bone voids following trauma, reconstruction in orthopedics, and spinal surgery
Cerabone®	Botiss	Sintered bovine bone granules	Sinus lift, horizontal and vertical augmentation, ridge preservation, peri-implant defects, socket preservation, bone defect augmentation, periodontal intrabony defects, furcation defects
Endobon®	Biomet 3i LLC	Fully deproteinized bovine hydroxyapatite	Alveolar ridge augmentation, sinus elevation, filling bone defects after root resection, socket filling after tooth extraction
CopiOs®	Zimmer	Mineralized particulate cancellous bovine bone chips	Large and small bone defects
Bonefill®	Bioinnovations Inc	Natural bovine bone mineral extracted from bovine femur	Bone failure reconstructions where remodeling or bone neoformation is desired
InterOss®	Sigmagraft	Natural bovine hydroxyapatite	Bone defect filling
Apatos OsteoBiol®	Tecnoss	Heterologous cortico-cancellous bovine bone mix	Large maxillofacial bone defects, reconstruction, or corrections
GenOx Org®	Braumer	Lyophilized porous organic matrix extracted from the bovine cortical bone	Procedures of dental implant, Maxillofacial and bone surgery in general
Cerabone®	aap Implantate AG	Cancellous bovine bone	Permanent bone filling or reconstruction of aseptic bone defects
OssiGuide®	Collagen Matrix	Cancellous bovine bone	Filling bony voids or gaps of the skeletal system that are not intrinsic to the stability of the bony structure
THE Graft®	Purgo Biologics	Porcine cancellous granules	Extraction socket with intact socket, extraction socket with defective socket, minor bone, augmentation, major bone augmentation, sinus floor elevation, peri-implantitis
Gen-Os®	Tecnoss	Cortico-cancellous heterologous porcine or equine bone mix	Alveolar ridge preservation, lateral access maxillary sinus lift, dehiscence regeneration
MatrixOss®	Collagen Matrix	An organic porcine bone mineral with carbonate apatite structure	Bone filling
Sp-Block	Tecnoss	Equine cancellous bone	When a vertical gain in posterior mandible is required
BIO-GEN® BIO-GEN® MIX GEL BIO-GEN® PUTTY	BioTECK	Equine cortical bone or spongy bone	Bone regeneration surgery
Alpha-Bio’s Graft	Alpha-Bio Tec	Bovine cancellous bone + bioactive resorbable polymers	Open sinus floor augmentation, peridontal intrabony defects, peri-implant bony defects, socket preservation, vertical and horizontal bone augmentations
Bio-Oss Collagen®	Geistlich	Deproteinized bovine bone mineral small granules +10% porcine collagen	Extraction socket management, minor bone augmentation, periodontal regeneration
Gel 40 Putty mp3®	Tecnoss	Porcine or equine Cortico-cancellous heterologous bone mix + different proportions of Collagen gel	Lateral and crestal access sinus lift, deep and narrow peri-implant defects, three-wall intrabony defects, gingival recessions, post-extractive sockets, defects that present a self-contained cavity
OsteoBiol® GTO®	Tecnoss	Porcine or equine heterologous cortico-cancellous bone mix + OsteoBiol® TSV Gel	Horizontal augmentation procedures, socket preservation

² Compositional details and intended uses were taken from the corresponding companies’ websites.