Figure 2.

Cytoplasmic expression of the APEX1 protein in 131 paired cases of hepatocellular carcinoma cells and the matched nontumor hepatocytes (A), 32 paired cases of intrahepatic cholangiocarcinoma cells and the matched nontumor bile duct epithelial cells (B), and 106 paired cases of clear cell renal cell carcinoma cells and the matched nontumor proximal convoluted tubular epithelial cells (C), using immunohistochemical staining for formalin-fixed, paraffin-embedded tissue (Wilcoxon signed-rank test: p < 0.001, each). The line in the middle of the boxes is the median. The box length indicates the interquartile range. The ends of the whiskers represent maximum and minimum values.