Table 2.
Summary of the clinicopathologic characteristics of patients with primary clear cell renal cell carcinoma (n = 106).
| Characteristics | No. | Nuclear APEX1 | Cytoplasmic APEX1 | ||
|---|---|---|---|---|---|
| Median (IQR) | p * | Median (IQR) | p * | ||
| Age at operation | 0.778 | 0.778 | |||
| ≤65 | 54 | 7 (7–7) | 2 (0–4) | ||
| >65 | 52 | 7 (6.25–7) | 2 (0–3.75) | ||
| Sex | 0.885 | 0.383 | |||
| Male | 75 | 7 (7–7) | 2 (0–3) | ||
| Female | 31 | 7 (7–7) | 2 (0–5) | ||
| Histologic nuclear grade | 0.016 | <0.001 | |||
| I–II | 72 | 7 (7–7) | 0 (0–2) | ||
| III–IV | 34 | 7 (5.75–7) | 4.5 (2–6) | ||
| Pathologic T stage | 0.189 | 0.512 | |||
| I | 44 | 7 (7–7.75) | 2 (0–4.75) | ||
| II–IV | 62 | 7 (6.75–7) | 2 (0–3) | ||
* Mann-Whitney U test; IQR, interquartile range; nuclear APEX1, nuclear expression of APEX1 protein in cancer cells; and cytoplasmic APEX1, cytoplasmic expression of APEX1 protein in cancer cells.