Figure 3.

Dose-dependent effect of PtNPs, DOX, and CIS on U2OS cell proliferation. U2OS cell proliferation was determined after exposure to different concentrations of (A) PtNPs (5–25 µg/mL) or (B) DOX (1–5 µg/mL) or (C) CIS (5–25 µg/mL) for 24 h. Results are expressed as the mean ± standard deviation of three independent experiments. Differences between the treated and control groups were measured using Student’s t-test and statistically significant differences are indicated by * (p < 0.05). The results are presented as mean ± standard deviation of three experiments. * p < 0.05 was considered significant; ** p < 0.01 was considered highly significant and *** p < 0.001 was considered very highly significant.