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. 2019 Aug 17;7(8):268. doi: 10.3390/microorganisms7080268

Table 5.

Top 20 GO biological processes enriched from unique peptides in the C. perfringens challenge jejunum (compared to postbiotic and postbiotic plus C. perfringens challenge groups).

Biological Process Number of Proteins p-Value (False Discovery Rate)
regulation of immune response 20 3.90 × 109
protein metabolic process 38 1.15 × 108
cellular protein metabolic process 35 1.31 × 108
positive regulation of metabolic process 35 1.80 × 108
regulation of phosphate metabolic process 24 1.80 × 108
intracellular signal transduction 26 1.80 × 108
defense response 23 2.02 × 108
regulation of phosphorylation 22 2.02 × 108
positive regulation of immune response 16 2.02 × 108
immune response-regulating signaling pathway 15 2.44 × 108
regulation of protein modification process 24 2.47 × 108
protein phosphorylation 18 3.17 × 108
innate immune response 19 3.93 × 108
regulation of immune system process 22 4.69 × 108
activation of immune response 14 5.11 × 108
response to nitrogen compound 18 8.11 × 108
immune response-activating signal transduction 13 1.35 × 107
Fc receptor signaling pathway 11 1.35 × 107
Fc-epsilon receptor signaling pathway 10 1.46 × 107
regulation of protein phosphorylation 20 1.60 × 107

Proteins statistically significantly differentially phosphorylated uniquely in the jejunal tissue samples from the C. perfringens challenge treatment group were pulled out of the array data and input into STRING for analysis. The resulting table of biological processes contained 258 terms enriched in the data. The top 20 by false discovery rate are shown in this table. Bold type indicates processes related to immune response.