Table 9.
KEGG pathways enriched from unique peptides in the postbiotic plus C. perfringens challenge jejunum (compared to postbiotic and C. perfringens challenge).
| KEGG Pathway | Number of Proteins | p-Value (False Discovery Rate) |
|---|---|---|
| AMPK signaling pathway | 7 | 4.40 × 106 |
| Acute myeloid leukemia | 5 | 3.23 × 105 |
| Chemokine signaling pathway | 6 | 0.000441 |
| Insulin signaling pathway | 5 | 0.00125 |
| PI3K-Akt signaling pathway | 6 | 0.00685 |
| Leukocyte transendothelial migration | 4 | 0.00685 |
| Pathways in cancer | 6 | 0.00685 |
| mTOR signaling pathway | 3 | 0.0146 |
| ErbB signaling pathway | 3 | 0.0329 |
| Endocytosis | 4 | 0.0329 |
| Fc gamma R-mediated phagocytosis | 3 | 0.0329 |
| Regulation of actin cytoskeleton | 4 | 0.0397 |
| Proteoglycans in cancer | 4 | 0.0405 |
| Thyroid cancer | 2 | 0.0405 |
Proteins statistically significantly differentially phosphorylated uniquely in the jejunal tissue samples from the postbiotic plus C. perfringens challenge treatment group were pulled out of the array data and input into STRING for analysis. The resulting table of KEGG pathways is shown above. Less than 20 significant pathways (false discovery rate) were generated. Highlighted in bold type are the pathways related to immune response.