Figure 1.

Effects of hispidin and H₂O₂ on the viability of Adult Retinal Pigment Epithelial cell line-19 (ARPE-19) cells. (A) ARPE-19 cells were treated with various concentrations (2.5–50 μM) of hispidin or (B) H₂O₂ (100–500 μM) for 24 (□) and 48 h (■), respectively. Cell survival was measured by MTT assay (C) ARPE-19 cells were pre-treated with hispidin (0–20 μM) for 24 h, followed by 300 μM H₂O₂ treatment for 24 h, cell survival was measured by MTT assay. ** p < 0.01 versus vehicle control.