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. 2019 Aug 8;8(8):326. doi: 10.3390/foods8080326

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Changes in cell viability (a), intracellular triglyceride content (b), reactive oxygen species production (c), and mRNA expression of NOX4, SOD2, catalase (CAT), and GPx enzymes (d) as well as leptin (LEP) (e) and adiponectin (ADIPOQ) (f) expression upon the treatment of3T3-L1 mature adipocytes with the elderberry fruit extract (EDBE). The photos present 3T3-L1 preadipocytes (g), fully differentiated 3T3-L1 adipocytes non-treated (h) and treated with EDBE at the concentration of 20 mg/mL (i). The cells were photographed at magnification of 100 ×. The results were expressed as the means ± SD (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control group.