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. 2019 Jul 29;11(8):1743. doi: 10.3390/nu11081743

Figure 2.

Figure 2

Effect of EGCG treatment on body weight, disease activity index (DAI) score, macroscopic severity score, and colon length following DSS-induced colitis. Both high and low doses of EGCG treatment significantly improved DSS-induced (A) body weight loss, (B) DAI score, (C) macroscopic severity score (MSS). High-dose EGCG markedly restored (D) colon length. Body weight changes were measured daily and calculated as the percentage change from Day 0. DAI scores were assessed from Day 1 to Day 12. MSS and colon length were evaluated at the end of the study. BW: Body weight, DAI: Disease activity index, DSS: Dextran sulfate sodium, EGCG: Epigallocatechin gallate, MSS: Macroscopic severity score, PBS: Phosphate buffered saline; NC: Normal control group, MD: Colitis model group, HE: High-dose EGCG group, LE: Low-dose EGCG group. Data are presented as mean ± standard deviation. * p < 0.05 vs. MD, ** p < 0.01 vs. MD, *** p < 0.001 vs. MD, ## p < 0.01 vs. NC.