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. 2019 Jul 29;11(8):1743. doi: 10.3390/nu11081743

Figure 4.

Figure 4

Effect of EGCG treatment on intestinal permeability (A), and myeloperoxidase (MPO) levels (B) in DSS-induced colitis. Intestinal permeability was measured using the fluorescein isothiocyanate conjugated dextran (FITC-dextran) assay on Day 12. At the end of the study, the colon was harvested and divided equally into three parts. MPO levels in the distal part of the colonic tissue was measured as a marker of neutrophil infiltration. DSS treatment significantly increased serum FITC-dextran levels and colon tissue MPO levels. Both high-and low-dose EGCG treatment decreased serum FITC-dextran levels and colonic tissue MPO levels significantly. FITC-dextran: Fluorescein isothiocyanate conjugated dextran, MPO: Myeloperoxidase; NC: Normal control group, MD: Colitis model group, HE: High-dose EGCG group, LE: Low-dose EGCG group. Data are presented as mean ± standard deviation. ** p < 0.01 vs. MD, *** p < 0.001 vs. MD, # p < 0.05 vs. NC, ### p < 0.001 vs. NC.