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. 2019 Sep 2;322(13):1271–1282. doi: 10.1001/jama.2019.14231

Figure 2. Eight-Year Cumulative Incidence Estimates (Kaplan-Meier) for 2 Composite End Points.

Figure 2.

The primary end point was the incidence of extended major adverse cardiovascular events (MACE; composite of 6 outcomes), defined as first occurrence of coronary artery events, cerebrovascular events, heart failure, atrial fibrillation, nephropathy, and all-cause mortality, recording the first occurrence after the index date as the event date. The secondary composite end points included 3-component MACE (all-cause mortality, myocardial infarction, and ischemic stroke), recording the first occurrence after the index date as the event date. For both end points, the median observation time was 4.0 years (interquartile range [IQR], 2.1-6.1) for nonsurgical patients and 3.3 years (IQR, 1.2-6.3) for surgical patients. HR indicates hazard ratio.