Fig. 4.

Effect of IFN-α on sociability in NZB/NZW F1 mice, as assessed by the social dominance tube test and the three-chamber social interaction test. a Graph showing the percentage of wins in the tube test. Number of animals per group: n = 10. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 vs. Adv-ctrl-treated group, unpaired t test. b Illustrative example of the travel path of a control mouse and an IFN-α-treated mouse in the three-chamber interaction test. c Percentage of time spent in the two chambers. Two-way ANOVA with Sidak’s test