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. 2019 Sep 3;19:872. doi: 10.1186/s12885-019-6072-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Imaging findings 4 years following denosumab treatment. a and b Plain radiographs showed shrinkage of the lesions with striking marginal sclerosis. c-g Fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography showed that each lesion had become less FDG-avid with a maximum standardized uptake value of 2.6 and was accompanied by remarkable sclerotic bone