Table 3.

Characterization of circRNAs that could be diagnostic biomarkers of osteosarcoma.

CircRNA	Deregulation	Genes/proteins affected	Diagnostic value
Circ_0008717 [17]	Overexpression	miR-203/Bmi-1	AUC value: 0.782, sensitivity value: 0.8, specificity value: 0.73
circRNA_ CDR1as [26]	Overexpression	miR-7	AUC value: 0.857
Circ-NT5C2 [29]	Overexpression	miR-448	AUC value: 0.753
circ_HIPK3 [33]	Overexpression	/	Cutoff value: 29.3, sensitivity value: 0.56, specificity value: 0.84
CircPVT1 [35]	Overexpression	Gene ABCB1	AUC value: 0.871
Circ_0081001 [36]	Overexpression	/	AUC value: 0.898