Figure 3.

Characteristics of peptides in the training set. (A) Sequence logos of immunogenic peptides (top), HeLa self-peptides (middle), and HLA-A2 non-binding peptides (bottom). (B) Comparison of the hydrophobicity of each peptide position in the immunogenic and self-peptide datasets (shown as the difference between the immunogenic and self-peptide datasets) as determined using the Wimley-White hydropathy index. Values less than zero (below dashed line) indicate greater hydrophobicity in the immunogenic dataset. P-values are indicated where the differences are statistically significant.