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. Author manuscript; available in PMC: 2020 May 7.
Published in final edited form as: Structure. 2019 Mar 21;27(5):794–805.e4. doi: 10.1016/j.str.2019.03.002

Figure 5. View of the CoQ-Binding Pocket and the Proposed Mechanism for Electron Transfer from Reduced FAD to DCQ.

Figure 5.

(A) Carbons in residues in the CoQ-binding pocket are colored according to residue type: nonpolar, white; negatively charged, magenta; positively charged, orange; polar, blue; carbons in DCQ are colored green. Hydrogen bonds are indicated by dashed yellow lines.

(B) The arrow shows the single through-space jump from FAD:O2 to DCQ:C3M predicted by the program HARLEM. Trp435:NH1, Ser378:O, and a water molecule are proposed to act as proton donors or acceptors, as discussed in the text.

See also Figures 2A and 2B.