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. Author manuscript; available in PMC: 2020 May 7.
Published in final edited form as: Structure. 2019 Mar 21;27(5):794–805.e4. doi: 10.1016/j.str.2019.03.002

Scheme 1. Catalytic Mechanism of Human SQOR.

Scheme 1.

Proposed mechanism for the reaction catalyzed by human SQOR in the presence of a sulfane sulfur acceptor, denoted N: (steps 1–5) and a postulated slow conversion of 4a-adduct I to thiocystine in the absence of N: (steps 6–7) (Jackson et al., 2012).