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. 2019 Aug 28;12:200. doi: 10.3389/fnmol.2019.00200

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Copyright © 2019 Sackmann, Sinha, Sackmann, Civitelli, Bergström, Ansell-Schultz and Hallbeck.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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nSMase2 siRNA downregulates the SMPD3 gene, and ESCRT-dependent genes are upregulated under hypoxia. RT-PCR analysis of common ESCRT genes and SNCA (α-syn) in donor cells. Changes in the expression levels are displayed from blue (downregulated) to red (upregulated), with the values representing the mean fold change relative to control samples (n = 3). The complete RT-PCR data are available in Supplementary Table S1.