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. 2005 May 11;25(19):4706–4718. doi: 10.1523/JNEUROSCI.4520-04.2005

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Copyright © 2005 Society for Neuroscience 0270-6474/05/254706-13.00/0

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Figure 9. — APα-induced proliferation of neural progenitor cells requires activation of the L-type calcium channel. MuLV-GFP viral particle-infected rat hippocampal neurons were treated with vehicle, nifedipine (an L-type calcium channel antagonist), APα, or APα plus nifedipine. Nifidipine (10 μm) completely abolished the proliferative effect of APα, which was detected by FACS analysis of GFP-positive cells. Data are from three independent experiments and presented as percentage of GFP-positive cells in each group versus control (set as 100%). ^*p < 0.01 versus control, nifedipine, or APα plus nifedipine.