Figure 3.

Effects of hippocampal AP-5 and CNQX infusions on encoding and retrieval of one-trial place memory (experiment 3, n = 14 rats). The percentage dig time at correct and novel sandwells (mean ± 1 SEM) in probe trials is presented as a performance measure; stippled horizontal lines indicate chance. A, Performance when the NMDA receptor antagonist d-AP-5 (30 mm, 1 μl) or ACSF (1 μl) was infused into the hippocampus 15 min before the encoding or retrieval phase. B, Performance when the AMPA receptor antagonist CNQX (3 mm, 1 μl) or ACSF (1 μl) was infused 15 min before the retrieval phase.