Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2005 Jun 22;25(25):5975–5983. doi: 10.1523/JNEUROSCI.0804-05.2005

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2005 Society for Neuroscience 0270-6474/05/255975-09.00/0

PMC Copyright notice

Figure 7. — RIM localization is partially dependent on ELKS. A, The PDZ and C2A domains of RIM are sufficient for RIM localization. GFP (green) and ELKS (red) immunostaining in the ventral nerve cord of transgenic unc-10(md1117) animals expressing GFP-PDZC2A_RIM (GFP-tagged RIM containing amino acids 627-974) or GFP-C2A_RIM (GFP-tagged RIM containing amino acids 826-974) is shown. B, The localization of GFP-PDZC2A_RIM is ELKS dependent. GFP (green) and ELKS (red) immunostaining in the ventral nerve cord of transgenic elks(js816); unc-10(md1117) expressing GFP-PDZC2A_RIM. C, RIM localizes in the absence of ELKS and other active zone components. RIM immunostaining in the dorsal nerve cord of unc-13(s69); elks(js816), elks(js816); unc-2(e55), and elks(js816); syd-2(ju37) double-mutant animal is shown. Scale bars, 20 μm.