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. 2005 Jun 15;25(24):5796–5802. doi: 10.1523/JNEUROSCI.0824-05.2005

Figure 4.

Figure 4.

BDNF increases the frequency and amplitude of sGABAA-PSCs. A, Traces from a single experiment showing sGABAA-PSCs (holding potential, -70 mV) recorded before (left) and 10 min after (right) BDNF onset (20 ng/ml). B, Time course of the effect of BDNF on the frequency of sGABAA-PSCs (bin, 1 min; same cell as in A). C, Cumulative probability plot of the sGABAA-PSCs amplitude (same cell as in A) before (open circles) and 10 min after (filled circles) the onset of BDNF (p < 0.05; K-S test). D, Summary plot of the effect of BDNF on sGABAA-PSC frequency versus time in control (n = 9) and in slices preincubated with 5 μg/ml TrkB-IgG (n = 8). E, The histogram shows the average change in the amplitude (open bar) and frequency (filled bar) of sGABAA-PSCs induced by BDNF in control slices (n = 9), after 20 min of BDNF washout (n = 9), and in slices preincubated with 5 μg/ml TrkB-IgG (n = 8; *p < 0.05 compared with before BDNF application; Student's t test).