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. 2005 Mar 30;25(13):3294–3303. doi: 10.1523/JNEUROSCI.4175-04.2005

Figure 5.

Figure 5.

L-LTP induced by β-adrenergic receptor activation paired with subthreshold stimulation is independent of transcription. A, Application of ACT-D did not inhibit L-LTP elicited by pairing 5 Hz with ISO (filled squares). B, Application of ACT-D did not inhibit L-LTP elicited by pairing 1 × 100 Hz stimulation with ISO (filled squares). C, Application of ISO during 5 Hz generated L-LTP in isolated CA1 pyramidal cell dendrites (filled squares). D, Application of emetine to cut slices treated with ISO and 5 Hz inhibited the maintenance of L-LTP (filled triangles). E, Summary histogram comparing effects of applying ACT-D and emetine to isolated CA1 pyramidal dendrites (cut slices) (**p < 0.01). All sample traces were taken 10 min after commencement of baseline recording and 120 min after stimulation protocol. Calibration for cut slices: 2 mV, 2 ms. Calibration for intact slices: 5 mV, 2 ms.