Table 1.
Results from choline uptake assays and CHT immunoblotting analyses (mean ± SEM)
|
|
Right mPFC |
Left mPFC |
Right posterior cortex |
Left posterior cortex |
Striatum |
||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Task |
Vmax (pmol·mg−1·5 min−1) |
Km2 (μm) |
LP1/LP1 + LP2 (AU) |
Vmax (pmol·mg−1·5 min−1) |
Km2 (μm) |
LP1/LP1 + LP2 (AU) |
Vmax (pmol·mg−1·5 min−1) |
Km2 (μm) |
LP1/LP1 + LP2 (AU) |
Vmax (pmol·mg−1·5 min−1) |
Km2 (μm) |
LP1/LP1 + LP2 (AU) |
Vmax (pmol·mg−1·5 min−1) |
Km2 (μm) |
LP1/LP1 + LP2 (AU) |
||||||||||
| NP | 14.72 ± 0.48 | 0.91 ± 0.02 | 0.31 ± 0.03 | 13.36 ± 0.68 | 1.05 ± 0.02 | 0.40 ± 0.02 | 15.25 ± 0.25 | 1.16 ± 0.02 | 0.40 ± 0.02 | 13.64 ± 0.45 | 0.88 ± 0.05 | 0.43 ± 0.01 | 37.13 ± 2.53 | 0.78 ± 0.10 | 0.42 ± 0.03 | ||||||||||
| SRTT | 19.43 ± 1.07 | 1.03 ± 0.04 | 0.43 ± 0.01 | 16.15 ± 1.32 | 1.16 ± 0.06 | 0.33 ± 0.01 | 16.04 ± 1.00 | 1.18 ± 0.05 | 0.36 ± 0.02 | 14.25 ± 0.54 | 1.12 ± 0.06 | 0.42 ± 0.02 | 28.11 ± 1.74 | 1.19 ± 0.03 | 0.37 ± 0.03 | ||||||||||
| CVT |
23.58 ± 0.58*
|
1.12 ± 0.03 |
0.50 ± 0.03*
|
15.52 ± 0.65 |
1.05 ± 0.03 |
0.34 ± 0.02 |
17.07 ± 0.92 |
0.83 ± 0.04 |
0.40 ± 0.02 |
13.73 ± 0.57 |
1.11 ± 0.03 |
0.46 ± 0.02 |
38.75 ± 1.91 |
0.96 ± 0.04 |
0.46 ± 0.03 |
||||||||||
AU, Arbitrary units.
*
Significantly different from NP data, based on Tukey's honestly significant difference (p < 0.05).