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Nedd8 mutant MB clones show axon terminal morphogenetic defects. Wild-type (WT; A, B) and Nedd8AN015 mutant (C, D) clones of MB neurons, generated in NHL, were examined in adults. Only a small number of γ neurons exist in the mutant Nb clone (C), and most mutant γ axons stall before reaching the midline (e.g., arrows in C and D). Genotype: A, B, hs-FLP/X;UAS-mCD8-GFP,FRT40A/tubP-GAL80,FRT40A;GAL4-OK107/+; C, D, hs-FLP,UAS-mCD8-GFP/X;Nedd8AN015,FRT40A/tubP-GAL80, FRT40A;GAL4-OK107/+.
