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. 2005 Jun 1;25(22):5314–5322. doi: 10.1523/JNEUROSCI.0687-05.2005

Figure 4.

Figure 4.

Percentage increase in the number of c-Fos-immunoreactive cells in the brains of SEA-challenged wild-type (TNF+/+; n = 6) and TNFα knock-out (TNF-/-; n = 5) mice. For each individual animal that was given an injection of SEA, the quantitation for each brain region was expressed as a percentage above the group mean of the corresponding saline-injected control of the same strain. The mean number of c-Fos-positive cells in wild-type saline-injected (n = 5) (see Fig. 1) and saline-injected TNFα knock-out mice (n = 5) did not differ (mean ± SE for TNF knock-out saline: PVN, 60 ± 34; arcuate nucleus, 55 ± 12; LS, 58 ± 36; BNST, 10.7 ± 2.2; ceA, 8.9 ± 1.9). *p < 0.05 (unpaired Student's t test) relative to the mean percentage of change of the TNFα knock-out group. Arc, Arcuate nucleus.