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. 2005 Jun 29;25(26):6084–6091. doi: 10.1523/JNEUROSCI.0542-05.2005

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Copyright © 2005 Society for Neuroscience 0270-6474/05/256084-08.00/0

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Figure 3. — ACh-induced action potential bursts preceding the STP paradigm produced LTP or LTD. A, When the ACh-induced (horizontal bar) burst continued until the electrical stimulation (stim) was applied (upward arrows), then LTP resulted, as indicated by the time course below. The representative PSPs are from the indicated times. Calibration: 0.5 s, 20 mV for the depolarization; 50 ms, 2 mV for the PSPs. B, The representation is the same, but when the ACh-induced burst stopped within 1 s of the electrical stimulation, then LTD resulted, as indicated by the time course.