Table 1.
Exploratory behaviors and motor performance of wild-type and HD transgenic mice recorded from 3 min sessions in the open field and on the accelerating rotarod
|
Exploratory parameter |
Number of squares crossed |
|
Number of rears |
|
Time spent on the accelerating rotarod |
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (weeks) | 10 | 12 | 14 | 10 | 12 | 14 | 10 | 12 | 14 | |||
| Wild-type mice (n = 6) | 28.8 (5.6) | 34 (4) | 25 (9.1) | 5.2 (2.5) | 6.2 (0.9) | 6 (2.8) | 106.8 (23.4) | 109.3 (17.5) | 127.3 (18.4) | |||
| HD transgenic mice (n = 12) |
22.8 (3.4) |
31.5 (4.9) |
26.2 (5.2) |
4.5 (1) |
4.7 (1.2) |
5.3 (1.6) |
83 (11.3) |
82.4 (13.5) |
87.3 (17.5) |
|||
Data are presented as mean (SEM).