Table 1.
Effect of dietary treatment on docosatetraenoic (22:4n6) acid levels in Tg2576 mice
|
|
Dietary PUFA |
Brain DTA |
||||
|---|---|---|---|---|---|---|
| Diet group |
DHA % w/w |
n-6/n-3 ratio |
Tg |
Non-Tg |
||
| Control (n = 8) | 0.09 | 7:1 | 2.41 ± 0.08 | 2.6 ± 0.06 | ||
| Low DHA (n = 6) | <0.01 | 85:1 | 2.78 ± 0.12* | 2.76 ± 0.10 | ||
| High DHA (n = 6) |
0.6 |
5:1 |
1.74 ± 0.11**
|
1.97 ± 0.09**
|
||
Units are mean percentage of total fatty acids. *p<0.01 when compared with control chow group; **p<0.0001 when compared with low-DHA group. DTA, Docosatetraenoic acid.