Figure 2.

Regionalization of the early-neuronogenic Foxg1^-/- cortical primordium. The distribution of Otx2 (a, a′, j, j′), Wnt3a mRNA (b, b′, k, k′), Id3 mRNA(c, c′, l, l′), Wnt5a mRNA (d, d′, m, m′), Lef1 mRNA (e, e′, n, n′), Fzd9 mRNA (f, f′, o, o′), Emx1 (g, g′, p, p′), Fzd8 mRNA (h, h′, q, q′), and Tbr2 mRNA (i, i′, r, r′) on rostral (a-i′) and caudal (j-r′) frontal sections of Foxg1^-/- (a-r) and wild-type (a′-r′) E11.5 telencephalons is shown. Arrowheads in a-g′ and j-o′ point to the ventrolateral border of each pallial expression domain. The asterisk in a corresponds to the rostroventral Otx2 expression subdomain peculiar to Foxg1^-/- mutants. Asterisks in h′, i′, q′, and r′ demarcate lateral ventricular expression domains of Fzd8 and Tbr2, specific to wild-type brains. Scalebars, 200 μm.