Figure 1.
Bath application of TMR-SubP (500 nm) reversibly increases the frequency of endogenous inspiratory-related bursts generated by medullary slice preparations. The left panel depicts medullary slice. The top trace shows rectified and integrated recordings of XII nerve activity from a postnatal day 2 slice before, during, and after bath application of TMR-SubP. Rhythmic activity persisted for at least 4 h after application of TMR-SubP. Bottom traces show extended traces from times indicated by a and b in the top trace (i.e., before and during application of TMR-SubP).