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. 2005 Mar 9;25(10):2702–2711. doi: 10.1523/JNEUROSCI.5173-04.2005

Figure 7.

Figure 7.

Localization of wild-type and mutant CD47 proteins in cultured rat hippocampal neurons. A-C, Neurons were transfected with expression vectors for wild-type mCD47 (CD47-WT) (A), the mCD47 mutant CD47ΔCterm (B), or the chimeric protein CD8-CD47MMS (C) at 12 DIV. They were fixed and immunostained with mAbs to mCD47 (A, B) or to human CD8 (C) at 14 DIV. Scale bar, 50 μm. Data are representative of three separate experiments. D, Quantitation of the axon/dendrite fluorescence ratio for exogenously expressed GFP, wild-type mCD47, CD47ΔCterm, or CD8-CD47MMS. Data are means ± SE of values from 8 to 15 different cells. *p < 0.05 for the indicated comparison (Student's t test). n.s., Not significant.