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SynCAM-induced increase in mini frequency is specific to excitatory synapses. Bar graphs depict the mean frequencies of spontaneous miniature synaptic events recorded in the presence of TTX. Excitatory events (left) were isolated by the addition of 50 μm picrotoxin to the recording medium. Inhibitory events (right) were recoded after the addition of 10 μm CNQX (NL1, n = 3; SynCAM, n = 7; vector alone, n = 6).
