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Relationship between placebo-induced regional μ-opioid system activation and expectation of analgesia. Negative correlation between the expected analgesic effects as rated by the volunteers before the study and the placebo-induced activation of dorsolateral prefrontal cortex (DLPFC) μ-opioid neurotransmission in placebo responders (black circles) and nonresponders (gray circles) are shown. BP, Binding potential.
