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. 2005 Aug 10;25(32):7342–7351. doi: 10.1523/JNEUROSCI.4603-04.2005

Figure 8.

Figure 8.

Dopamine attenuates synaptic GluR1 expression during NMDA receptor stimulation. A, DA attenuates the increase in GluR1 surface expression produced by glycine (10 μm). Cultures were treated with medium, DA (1 μm), or glycine (10 μm). Cultures in the DA→glycine group were treated with DA for 10 min, rinsed, and treated for 3 min with glycine. The order of drug exposure was reversed in the glycine→ DA group (a, p < 0.05 compared with control group; b, p < 0.05 compared with glycine group; Dunn's test; n = 21-34). B, DA attenuates the increase in GluR1 synaptic incorporation produced by glycine (10 μm). Data are from the same experimental groups as in A. Results are presented as the percentage of the total SB area that overlaps with GluR1 area, normalized to the control group (a, p < 0.05 compared with control group; b, p < 0.05 compared with glycine group; Dunn's test; n = 21-34). Error bars indicate SEM.