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Changes in CA3 cells during the first and second sessions in the novel environment. Aged CA3 cells demonstrated less change than young CA3 cells during both sessions in the novel environment. Only CA3 cells are shown. A, Firing rate change. B, Maximum firing rate change. C, Place field similarity. Statistical significance, *p < 0.05 for comparison within aged CA3 of the first and second sessions. fam1, Familiar1; fam2, familiar2. Error bars represent SEM.
