Figure 1.
Kinetics of quantal events in Purkinje cells and Bergmann glial cells. A, CFs stimulated in the presence of 1.0 mm Sr2+/1.3 mm Mg2+ evoked asynchronously occurring quantal events in voltage-clamped PCs (Vh = -70 mV). Top trace, Example of a single epoch; middle traces, superimposition of the asynchronous events of five epochs at higher gain; bottom trace, average waveform of quantal responses collected from this cell. B, PC responses, as in A, after two PF stimuli (20 ms interval) in the presence of 2.0 mm Ca2+/1.3 mm Mg2+. C, BG responses to CF stimulation in the presence of 5 mm Sr2+ and 200 μm CTZ (Vh = -65 mV). D, BG responses to two PF stimuli (20 ms interval) in the presence of 2.0 mm Ca2+/1.3 mm Mg2+ and 200 μm CTZ. E, Summary of the peak conductance, the 20-80% rise time, and the decay time constant of quantal events recorded from PCs and BGs by stimulation of CFs and PFs (n = 5, 6, 4, and 7 cells for CF-PC, PF-PC, CF-BG, and PF-BG responses, respectively). Error bars represent SD.