Figure 5.

Recordings used to estimate the information-carrying capacity of the synapse. A, Mean (bold line) and three individual responses (light lines) from the postsynaptic neuron responding to an excerpt of the presynaptic wave form. B shows the excerpt from the presynaptic waveform. The voltage clamp ensured that the 2.4-s-long pseudorandom waveform was exactly replicated in each of 20 repetitions. C, Presynaptic current injected during one stimulus. To the left of A-C are brief periods when the presynaptic neuron was held clamped at dark resting potential. D, E, Probability distributions for mean postsynaptic response to 20 stimulus repetitions and for presynaptic potential during a 2.4 s stimulus waveform.