Figure 8.

Odor discrimination conditioning in 3-month-old (A) and 12-month-old (B) wild-type and α-mannosidase knock-out mice. Bars depict mean preference (and SEM) in wild-type (black bars) and knock-out (white bars) mice expressed as percentage of time spent digging in the target vial. The initial discrimination trials were less consistent in the knock-outs (open circles in preference plot, A), but additional training eventually stabilized their performance. Overall discriminatory and reversal performances were similar in both genotype groups (bar charts in A and B). C, Controls; KO, knock-outs.